| 2019 | American Eden: David Hosack, Botany, and Medicine in the Garden of the Early Republic | Victoria Johnson | Biography | 16 | 0 | 4 | Liveright | W. W. Norton & Company |
| 2020 | Every Living Thing: The Great and Deadly Race to Know All Life | Jason Roberts | Science | 14 | 2 | 2 | Random House | Penguin Random House |
| 2007 | Stanley: The Impossible Life of Africa's Greatest Explorer | Tim Jeal | Biography | 14 | 1 | 2 | Faber & Faber | Faber & Faber |
| 2003 | A Short History of Nearly Everything | Bill Bryson | Science | 14 | 1 | 2 | Random House | Penguin Random House |
| 1999 | Galileo's Daughter: A Historical Memoir of Science, Faith and Love | Dava Sobel | Biography | 14 | 1 | 2 | Fourth Estate | HarperCollins |
| 1994 | Naturalist | Edward O. Wilson | Memoir & Autobiography | 14 | 1 | 2 | Island Press | Island Press |
| 2016 | How to Survive a Plague: The Inside Story of How Citizens and Science Tamed AIDS | David France | Medicine & Public Health | 14 | 1 | 3 | Vintage Books | Penguin Random House |
| 2016 | Lab Girl | Hope Jahren | Memoir & Autobiography | 14 | 1 | 3 | Knopf Doubleday Publishing Group | Penguin Random House |
| 1983 | Black Apollo of Science: The Life of Ernest Everett Just | Kenneth R. Manning | Biography | 12 | 1 | 3 | Oxford University Press | Oxford University Press |
| 1992 | Genius: The Life and Science of Richard Feynman | James Gleick | Biography | 12 | 0 | 3 | Little, Brown | Hachette Book Group |
| 1989 | Berlioz: Volume 2 | David Cairns | Biography | 10 | 1 | 1 | Viking | Penguin Random House |
| 1983 | Weapons and Hope | Freeman Dyson | Politics & Government | 10 | 1 | 1 | Harper & Row | HarperCollins |
| 1975 | The Lives of a Cell: Notes of a Biology Watcher | Lewis Thomas | Science | 10 | 1 | 1 | Bantam Books | Penguin Random House |
| 1971 | The Blue Whale | George L. Small | Nature & Environment | 10 | 1 | 1 | Columbia University Press | Columbia University Press |
| 1953 | The Measure of Man | Joseph Wood Krutch | Society & Culture | 10 | 1 | 1 | Bobbs-Merrill | Bobbs-Merrill |
| 1939 | Wind, Sand and Stars | Antoine de Saint-Exupéry | Memoir & Autobiography | 10 | 1 | 1 | Reynal & Hitchcock | Reynal & Hitchcock |
| 1974 | LLife: The Unfinished Experiment | S. E. Luria | Science | 10 | 1 | 1 | Souvenir Press | Souvenir Press |
| 1937 | Madame Curie | Ève Curie | Biography | 10 | 1 | 1 | Unknown | Not yet sourced |
| 1981 | The Mismeasure of Man | Stephen Jay Gould | Science | 10 | 1 | 1 | W. W. Norton | W. W. Norton & Company |
| 2016 | Guilty Thing: A Life of Thomas De Quincey | Frances Wilson | Biography | 10 | 0 | 3 | Farrar, Straus and Giroux | Macmillan |
| 2021 | Fall: The Mystery of Robert Maxwell | John Preston | Biography | 8 | 1 | 2 | Viking | Penguin Random House |
| 2013 | Birth Certificate: The Story of Danilo Kiš | Mark Thompson | Biography | 8 | 1 | 2 | Cornell University Press | Cornell University Press |
| 1974 | Darwin on Man: A Psychological Study of Scientific Creativity | Howard E. Gruber, Paul H. Barrett | Science | 8 | 1 | 2 | Harvard University Press | Harvard University Press |
| 2025 | No More Tears: The Dark Secrets of Johnson & Johnson | Gardiner Harris | Journalism & Reportage | 8 | 0 | 2 | Random House | Penguin Random House |
| 2022 | Breathless: The Scientific Race to Defeat a Deadly Virus | David Quammen | Medicine & Public Health | 8 | 0 | 2 | Simon & Schuster | Simon & Schuster |
| 2014 | Deep Down Dark: The Untold Stories of 33 Men Buried in a Chilean Mine, and the Miracle That Set Them Free | Héctor Tobar | Journalism & Reportage | 8 | 0 | 2 | Sceptre | Hachette UK |
| 2010 | Alex's Adventures in Numberland: Dispatches from the Wonderful World of Mathematics | Alex Bellos | Science | 8 | 0 | 2 | Bloomsbury | Bloomsbury Publishing |
| 2000 | Darkness in El Dorado: How Scientists and Journalists Devastated the Amazon | Patrick Tierney | Journalism & Reportage | 8 | 0 | 2 | W. W. Norton | W. W. Norton & Company |
| 1992 | The Man Who Knew Infinity: A Life of the Genius Ramanujan | Robert Kanigel | Biography | 8 | 0 | 2 | Unknown | Not yet sourced |
| 2019 | Manual for Survival: A Chernobyl Guide to the Future | Kate Brown | Nature & Environment | 6 | 0 | 2 | W. W. Norton | W. W. Norton & Company |
| 2016 | When Breath Becomes Air | Paul Kalanithi | Memoir & Autobiography | 6 | 0 | 2 | Random House | Penguin Random House |
| 1991 | DDarwin | Adrian Desmond, James Moore | Biography | 4 | 1 | 1 | Unknown | Paladin |
| 2023 | I Would Meet You Anywhere: A Memoir | Susan Kiyo Ito | Memoir & Autobiography | 4 | 0 | 1 | Ohio State University Press | Ohio State University Press |
| 2022 | Virology: Essays for the Living, the Dead, and the Small Things in Between | Joseph Osmundson | Science | 4 | 0 | 1 | W. W. Norton | W. W. Norton & Company |
| 2021 | The Doctors Blackwell: How Two Pioneering Sisters Brought Medicine to Women and Women to Medicine | Janice P. Nimura | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 2021 | The Reason for the Darkness of the Night: Edgar Allan Poe and the Forging of American Science | John Tresch | Biography | 4 | 0 | 1 | Farrar, Straus and Giroux | Macmillan |
| 2017 | A Brief History of Everyone Who Ever Lived: The Human Story Retold Through Our Genes | Adam Rutherford | Science | 4 | 0 | 1 | W. W. Norton | W. W. Norton & Company |
| 2017 | Admissions: Life as a Brain Surgeon | Henry Marsh | Memoir & Autobiography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 2017 | The Seeds of Life: From Aristotle to da Vinci, from Sharks' Teeth to Frogs' Pants, the Long and Strange Quest to Discover Where Babies Come | Edward Dolnick | Science | 4 | 0 | 1 | Basic Books | Hachette Book Group |
| 2015 | Jonas Salk: A Life | Charlotte DeCroes Jacobs | Biography | 4 | 0 | 2 | Oxford University Press | Oxford University Press |
| 2013 | A Sting in the Tale: My Adventures with Bumblebees | Dave Goulson | Nature & Environment | 4 | 0 | 1 | Jonathan Cape | Penguin Random House |
| 2012 | Robert Duncan, The Ambassador from Venus: A Biography | Lisa Jarnot | Biography | 4 | 0 | 1 | University of California Press | University of California Press |
| 2010 | Secret Historian: The Life and Times of Samuel Steward, Professor, Tattoo Artist, and Sexual Renegade | Justin Spring | Biography | 4 | 0 | 1 | Farrar, Straus and Giroux | Macmillan |
| 2009 | Remarkable Creatures: Epic Adventures in the Search for the Origins of Species | Sean B. Carroll | Science | 4 | 0 | 1 | Houghton Mifflin Harcourt | Houghton Mifflin Harcourt |
| 2007 | Quantum: Einstein, Bohr and the Great Debate about the Nature of Reality | Manjit Kumar | Science | 4 | 0 | 1 | HarperCollins | HarperCollins |
| 2005 | A Sense of the World: How a Blind Man Became History’s Greatest Traveler | Jason Roberts | Biography | 4 | 0 | 1 | Simon & Schuster | Simon & Schuster |
| 2003 | Isaac Newton | James Gleick | Biography | 4 | 0 | 1 | HarperCollins | HarperCollins |
| 2002 | Complications: A Surgeon's Notes on an Imperfect Science | Atul Gawande | Medicine & Public Health | 4 | 0 | 1 | Metropolitan Books | Macmillan |
| 2002 | Edison’s Eve: A Magical History of the Quest for Mechanical Life | Gaby Wood | Science | 4 | 0 | 1 | Knopf | Penguin Random House |
| 2000 | The Monk in the Garden: The Lost and Found Genius of Gregor Mendel, the Father of Genetics | Robin Marantz Henig | Biography | 4 | 0 | 1 | Houghton Mifflin | Houghton Mifflin Harcourt |
| 1999 | At Home with the Marquis de Sade: A Life | Francine du Plessix Gray | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1995 | Marie Curie: A Life | Susan Quinn | Biography | 4 | 0 | 1 | Simon & Schuster | Simon & Schuster |
| 1995 | MMozart: A Life | Maynard Solomon | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1993 | Charles Sanders Peirce: A Life | Joseph Brent | Biography | 4 | 0 | 1 | Indiana University Press | Indiana University Press |
| 1987 | Timebends: A Life | Arthur Miller | Memoir & Autobiography | 4 | 0 | 1 | Grove Press | Grove Atlantic |
| 1978 | Germany, 1866–1945 | Gordon A. Craig | History | 4 | 0 | 1 | Oxford University Press | Oxford University Press |
| 1977 | A Species of Eternity | Joseph Kastner | Nature & Environment | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1975 | Minamata | W. Eugene Smith, Aileen M. Smith | Nature & Environment | 4 | 0 | 1 | Chatto & Windus | Penguin Random House |
| 1975 | Obedience to Authority: An Experimental View | Stanley Milgram | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1974 | H. G. J. Moseley: The Life and Letters of an English Physicist, 1887–1915 | J. L. Heilbron | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1973 | Bell: Alexander Graham Bell and The Conquest of Solitude | Robert V. Bruce | Biography | 4 | 0 | 1 | Cornell University Press | Cornell University Press |
| 1973 | Deaths of Man | Edwin S. Shneidman | Medicine & Public Health | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1973 | Genetic Fix: The Next Technological Revolution | Amitai Etzioni | Technology | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1969 | Life on Man | Theodor Rosebury | Science | 4 | 0 | 1 | Viking | Penguin Random House |
| 1969 | Technological Man | Victor C. Ferkiss | Technology | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1968 | A Portrait of Isaac Newton | Frank E. Manuel | Biography | 4 | 0 | 1 | Harvard University Press | Harvard University Press |
| 1968 | Lawrence and Oppenheimer | Nuel Pharr Davis | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1967 | Stop-Time | Frank Conroy | Memoir & Autobiography | 4 | 0 | 1 | Penguin Books | Penguin Random House |
| 1967 | The Biology of Ultimate Concern | Theodosius Dobzhansky | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1966 | The Language of Life: An Introduction to the Science of Genetics | George Beadle, Muriel Beadle, | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1965 | A Peril and a Hope: The Scientists' Movement in America, 1945–47 | Alice Kimball Smith | History | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1963 | The Last Horizon | Raymond Fredric Dasmann | Nature & Environment | 4 | 0 | 1 | Macmillan | Macmillan |
| 1948 | The Universe and Dr. Einstein | Lincoln Barnett | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1943 | TThe American Leonardo: The Life of Samuel F. B. Morse | Carleton Mabee | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1923 | From Immigrant to Inventor | Michael I. Pupin | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1974 | AAre Quanta Real?: A Galilean Dialogue | J. M. Jauch | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 2002 | Benjamin Franklin | Edmund S. Morgan | Biography | 4 | 0 | 1 | Viking | Penguin Random House |
| 1975 | Carrying the Fire: An Astronaut's Journeys | Michael Collins | Memoir & Autobiography | 4 | 0 | 1 | Ballantine Books | Penguin Random House |
| 1993 | Genius in the Shadows: A Biography of Leo Szilard, the Man Behind the Bomb | William Lanouette, Bela Silard | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1985 | In the Name of Eugenics: Genetics and the Use of Human Heredity | Daniel J. Kevles | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1974 | Sir Harry Vane: His Life and Times (1613–1662) | J. H. Adamson, H. F. Folland | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1975 | TThe Chasm: The Life and Death of a Great Experiment in Ghetto Education | Robert Jean Campbell, M.D. | Society & Culture | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1969 | TThe Double Helix: A Personal Account of the Discovery of the Structure of DNA | James D. Watson | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1926 | TThe Life of Sir William Osler, 2 vols. | Harvey Cushing | Biography | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1974 | TThe Saturday Night Special and Other Guns | Robert Sherrill | Politics & Government | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1980 | TThe Solar Age Resource Book | Solar Age magazine editors | Nature & Environment | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1970 | The Unexpected Universe | Loren Eiseley | Nature & Environment | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1975 | The Voyages of Apollo: The Exploration of the Moon | Richard S. Lewis | History | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1973 | TThe Will to be Human | Silvano Arieti, M.D. | Medicine & Public Health | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1988 | Three Scientists and Their Gods: Looking for Meaning in an Age of Information | Robert Wright | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1964 | Wasp Farm | Howard Ensign Evans | Nature & Environment | 4 | 0 | 1 | Unknown | Not yet sourced |
| 1965 | WWe Are Not Alone: The Search for Intelligent Life on Other Worlds | Walter S. Sullivan | Science | 4 | 0 | 1 | Unknown | Not yet sourced |
| 2008 | Samuel Johnson: The Struggle | Jeffrey Meyers | Biography | 4 | 0 | 2 | Basic Books | Hachette Book Group |
| 2015 | The Story of Alice: Lewis Carroll and the Secret History of Wonderland | Robert Douglas-Fairhurst | Biography | 2 | 0 | 1 | Vintage Books | Penguin Random House |