Empire of Pain: The Secret History of the Sackler Dynasty

Patrick Radden Keefe

The history of the Sackler dynasty is rife with drama—baroque personal lives; bitter disputes over estates; fistfights in boardrooms; glittering art collections; Machiavellian courtroom maneuvers; and the calculated use of money to burnish reputations and crush the less powerful. The Sackler name has adorned the walls of many storied institutions—Harvard, the Metropolitan Museum of Art, Oxford, the Louvre. They are one of the richest families in the world, known for their lavish donations to the arts and the sciences. The source of the family fortune was vague, however, until it emerged that the Sacklers were responsible for making and marketing a blockbuster painkiller that was the catalyst for the opioid crisis. Empire of Pain begins with the story of three doctor brothers, Raymond, Mortimer and the incalculably energetic Arthur, who weathered the poverty of the Great Depression and appalling anti-Semitism. Working at a barbaric mental institution, Arthur saw a better way and conducted groundbreaking research into drug treatments. He also had a genius for marketing, especially for pharmaceuticals, and bought a small ad firm. Arthur devised the marketing for Valium, and built the first great Sackler fortune. He purchased a drug manufacturer, Purdue Frederick, which would be run by Raymond and Mortimer.

BiographyBiography · high confidenceBiography81 signalsLlm Classifier: Biography -> BiographyOpen Library: Biography & Memoir -> Memoir & AutobiographyOpen Library: BIOGRAPHY & AUTOBIOGRAPHY / Rich & Famous -> Memoir & AutobiographyBusiness BiographyDisease, Epidemics & DrugsBusiness, Capitalism & Corporations
Experimental book profileGenerated by GPT-5.4 nano · may contain inaccuracies

This is an unverified interpretation of the catalog description, offered as an opt-in discovery experiment—not as bibliographic fact. Automated checks have flagged this profile for extra review.

  1. 01 Central figures

    • Raymond Sackler83%
    • Mortimer Sackler83%
    • Arthur Sackler93%
  2. 02 Central places

    None extracted with sufficient confidence.

    These suggestions did not meet the normal display threshold and are more likely to be wrong.

    • Harvard55%
    • Oxford45%
    • the Louvre40%
  3. 03 Suggested argument

    The Sackler dynasty’s fortune grew from making and marketing a blockbuster painkiller, which the book presents as a catalyst for the opioid crisis.

    Model confidence 72%

  4. 04 Reading orientation

    35 / 100 academic

    Serious trade

    An estimate of intended readership and scholarly apparatus—not quality or importance.

Confidence percentages are the model's own estimates. Profile confidence: 76%.