American Overdose: The Opioid Tragedy in Three Acts

Chris McGreal

"A comprehensive portrait of a uniquely American epidemic--devastating in its findings and damning in its conclusions. The opioid epidemic has been described as 'one of the greatest mistakes of modern medicine.' But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of 'drug dealers in white coats.' A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers--resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming.

Medicine & Public HealthMedicine & Public Health · high confidenceMedicine & Public Health81 signalsLlm Classifier: Medicine & Public Health -> Medicine & Public HealthOpen Library: MEDICAL / Pain Medicine -> Medicine & Public HealthOpen Library: SOCIAL SCIENCE / Disease & Health Issues -> Medicine & Public HealthClimate, Weather & DisasterDisease, Epidemics & DrugsDrugs, Addiction & TreatmentClass, Poverty & Inequality
Experimental book profileGenerated by GPT-5.4 nano · may contain inaccuracies

This is an unverified interpretation of the catalog description, offered as an opt-in discovery experiment—not as bibliographic fact.

  1. 01 Central figures

    None extracted with sufficient confidence.

  2. 02 Central places

    None extracted with sufficient confidence.

  3. 03 Suggested argument

    No argument inferred with sufficient confidence.

    This suggestion did not meet the normal display threshold and is more likely to be wrong.

    The opioid epidemic’s scale is driven by greed, corruption, and indifference—especially pharmaceutical influence over the FDA and Congress—rather than medical error alone.

    Model confidence 56%

  4. 04 Reading orientation

    34 / 100 academic

    Serious trade

    An estimate of intended readership and scholarly apparatus—not quality or importance.

Confidence percentages are the model's own estimates. Profile confidence: 63%.